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帕利斯特（Pallister）博士於1947年與妻子一起來到蒙大拿州（Montana）做全科醫生，並在一家弱智機構工作。在他任職期間，他參與了診斷工作，以為居民提供更好的護理和治療。
多年來，他吸引了許多學生，遺傳學家，外科醫生和其他專業人士來到該機構。隨著時間的流逝，Pallister醫師開始保存所有未進行診斷的患者的組織，以幫助日後進行診斷。
1963年，帕利斯特（Pallister）博士和內科醫生J.艾倫·米勒（J. Allen Miller）博士開始進行染色體分析。目前，該機構有兩名患者，一名三十多歲的男子和一名十六歲的女孩，他們具有許多相似的特徵，包括每名患者中發現的超小染色體。帕利斯特博士堅信他們有同樣的病情。經過與其他醫生的進一步研究，他們倆都被發現具有產生4個12號染色體短臂拷貝的同染色體。
現在被稱為Pallister-Killian馬賽克綜合症。帕利斯特（Pallister）博士親切地參加了2006年在費城兒童醫院舉行的第一次PKS醫學會議，會見了許多患有PKS的兒童家庭。帕利斯特和他的妻子威拉（Willie）育有15個孩子。
他和他的兒子亞當（Adam）也有最近發現的染色體異常，他住在蒙大拿州的山丘上。他們將大部分時間用於牧場，打獵，園藝和維修汽車，拖拉機和設備。
2014年7月11日，帕利斯特（Pallister）博士因在周年紀念中的傑出工作而受到嘉獎。
2018年3月9日，奧爾·菲爾（Ol'Phil）在家中去世。
In 1963 Dr. Pallister and physician Dr. J. Allen Miller began chromosome analyses. At this time, there were two patients in the institution, a man in his late thirties and a sixteen-year-old girl, who shared many similar characteristics including the extra small chromosome that was discovered in each patient. Dr. Pallister was convinced they had the same condition. After further study with other physicians, they were both found to have the isochromosome producing four copies of the short arm of chromosome 12.
It is now known as Pallister-Killian Mosaic Syndrome. Dr. Pallister graciously came to the first PKS medical conference held at The Children’s Hospital of Philadelphia in 2006 and met many families of children with PKS.Dr. Pallister and his wife Willa, “Willie” had 15 children.
He and his son Adam, who also has a recently discovered chromosome abnormality, lived in the hills of Montana. They spent most of their time working on the ranch, hunting, gardening, and repairing cars, tractors, and equipment.
On July 11, 2014, Dr. Pallister was feted for his outstanding work at a Jubilee in his honor.
On March 9, 2018, Ol' Phil passed away at home.